The band of rainfall happens at what is called the intertropical convergence zone. There, just north of the equator, trade winds from the northern and southern hemispheres collide at the same time heat pours into the atmosphere from the tropical sun. Rain clouds 30,000 feet thick in places proceed to dump as much as 13 feet (4 meters) of rain a year in some places. The band stretching across the Pacific is generally between 3 degrees and 10 degrees north of the equator depending on the time of year. It has recently been hypothesized that the intertropical convergence zone does not reside in the southern hemisphere for reasons having to do with the distribution of land masses and locations of major mountain ranges in the world, particularly the Andes mountains, that have not changed for millions of years.
Chen's team injected the spinal cords of mice with a neurotoxin called bombesin-saporin. It bound to GRPR and killed the neurons where the gene was expressed. When these mice then were exposed to things that caused itching, they didn't scratch. With an appropriate dose of the neurotoxin, their scratching could be reduced by more than 80 percent or completely eliminated in some instances. That finding proved that the neurons with GRPR were required for normal itch sensation.
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